Massive parallel sequencing of individual nucleic acid molecules enables large-scale, comprehensive and in-depth characterization of patient samples at a speed unachievable by conventional sequencing methods.
Molecular diagnostics is the most rapidly growing segment of the in vitro diagnostic market with next generation sequencing (NGS) providing the major technological platform for the state-of-the-art genomic screening of patient samples. NGS coupled with downstream bioinformatic analyses allows for the high-throughput detection of altered genomic regions, providing a wealth of clinically relevant data, which facilitates personalized precision medicine.
During the laboratory workflow, pooling of NGS libraries prepared from multiple individual samples is followed by massive parallel sequencing, which generates millions to billions of sequencing reads, thus producing a large amount of data for computational processing and bioinformatic analysis.
To support our customers’ diagnostic workflows, we provide end-to-end solutions consisting of a streamlined wet lab protocol combined with an easy-to-use intuitive bioinformatic analysis suite.
Oncology gene panels
The ViennaLab NGS gene panels are designed for diagnostic and research laboratories focusing on oncology and aiming to identify germline and somatic aberrations with clinical relevance in biopsy specimens. High-quality libraries are generated by a hybrid-capture target enrichment protocol and can be sequenced on NGS instruments from various manufacturers. Investigators can perform secondary and tertiary analyses on their own by using our webtool equipped with interactive graphical user interface and optimized, ready-to-use bioinformatic pipelines (included in the kit price).
Composition and diversity of the human gut microbiome have been linked to a wide range of phenotypes in health and disease. Targeted sequencing of the variable regions in the 16S rRNA gene provides a rapid and easy way to assess the bacterial composition in the human intestine. The ViennaLab 16S Microbiome NGS Assay in conjunction with the ViennaLab Microbiome Analysis Webtool offers a powerful end-to-end solution combining library preparation and bioinformatic analysis. Diversity statistics, informative summary tables and graphical output are generated to facilitate the rapid review and comprehensive evaluation of the bacterial composition in the analyzed samples.
NGS products for oncology