Dictionary of terms

All I


Immunoglobulin E is a type of antibody that has only been found in mammals. IgE is synthesised by plasma cells. Its main function is immunity to parasites such as helminths. IgE has an essential role in type I hypersensitivity, which manifests in various allergic diseases. IgE also plays a pivotal role in responses to allergens such as: anaphylactic reactions to drugs, bee stings, and antigen preparations used in desensitization immunotherapy.

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